The Protective Effects of Nigella sativa and Its Constituents on Induced Neurotoxicity

Table 3

The effect of Nigella sativa and TQ on epilepsy.

Drug	Dose	Result	References
N. sativa oil	4 mL/kg	Did not improve significantly the pilocarpine-induced abnormalities	[21]
N. sativa oil	12 mL/kg	Decreased the seizure score, protected against the convulsive behaviors and mortality, increased the GSH levels, and decreased the MDA level compared to the PTZ group	[22]
N. sativa	40 mg/kg	Mean frequency of seizures was decreased	[23]
TQ	200 and 400 mol	Reduced the duration of tonic-clonic seizures	[24]
TQ	40 and 80 mg/kg	Reduced the locomotor activity	[24]
TQ	1 mg/kg	Reduced the frequency of seizures	[25]