TY - JOUR A2 - Costa, Lucio Guido AU - Khazdair, Mohammad Reza PY - 2015 DA - 2015/10/29 TI - The Protective Effects of Nigella sativa and Its Constituents on Induced Neurotoxicity SP - 841823 VL - 2015 AB - Nigella sativa (N. sativa) is an annual plant and widely used as medicinal plant throughout the world. The seeds of the plant have been used traditionally in various disorders and as a spice to ranges of Persian foods. N. sativa has therapeutic effects on tracheal responsiveness (TR) and lung inflammation on induced toxicity by Sulfur mustard. N. sativa has been widely used in treatment of various nervous system disorders such as Alzheimer disease, epilepsy, and neurotoxicity. Most of the therapeutic properties of this plant are due to the presence of some phenolic compounds especially thymoquinone (TQ), which is major bioactive component of the essential oil. The present review is an effort to provide a comprehensive study of the literature on scientific researches of pharmacological activities of the seeds of this plant on induced neurotoxicity. SN - 1687-8191 UR - https://doi.org/10.1155/2015/841823 DO - 10.1155/2015/841823 JF - Journal of Toxicology PB - Hindawi Publishing Corporation KW - ER -