Research Strategies in the Study of the Pro-Oxidant Nature of Polyphenol Nutraceuticals

Figure 6

Comparative toxicities of pomegranate extract (PE) and olive fruit extract (OFE) towards human oral HSC-2 carcinoma cells, in Dulbecco’s modified Eagle medium (DMEM) commercially formulated without pyruvate (−pyr) and with pyruvate (+pyr). Cell proliferation was quantified with the neutral red assay, a cell viability assay. Data are presented as the mean percent of control ± S.E.M. Data for pomegranate extract are from Weisburg et al. [14] and for olive fruit extract from Schuck (unpublished).