Regulation and Function of Syk Tyrosine Kinase in Mast Cell Signaling and Beyond
Figure 1
Structure of protein tyrosine kinase Syk: (a) a schematic diagram of the linear structure of Syk with the tyrosines marked that are phosphorylated after its in vitro activation. In the linker region there are 23 amino acids which are missing in SykB. (b) Suggested globular structure of autoinhibited (left) and activated (right) Syk with some phosphorylated tyrosines indicated.
