Research Article

Investigating the Interaction of Nanodiamonds with Human Serum Albumin and Induced Cytotoxicity

Table 1

Various quenching constants, binding parameters, and thermodynamic parameters of HSA upon interaction with NDs at different temperatures.

SampleT (K)Kq × 109 (L·mol−1·s−1)mKb (L·mol−1)ΔG (kJ·mol−1)ΔH (kJ·mol−1)ΔS (J·mol−1·K−1)

HSA-ND2883.23/λ0.9314.9/λ0.93−6.33 + 2.22ln λ−19.67−46.31−8.31ln λm
2983.35/λ0.819.98/λ0.81−5.87 + 2.01ln λ
3033.54/λ0.768.85/λ0.76−5.64 + 1.91ln λ
3133.53/λ0.717.75/λ0.71−5.17 + 1.85ln λ