Research Article
Spectroscopic Characterization of Omeprazole and Its Salts
Table 5
Description and comparison of specific vibrations in Raman spectra of OMP and its salts.
| | Vibration | OMP | OMP-Li | OMP-Na | OMP-K | OMP-Mg | OMP-Ca |
| | O-H, stretching, H-bond | — | — | — | — | — | — | | O-H, stretching, free | — | — | — | — | — | — | | CH, stretching (BI, P) | 3076 | 3068 | 3070 | 3062 | 3066 | 3069 | | 3016 | 2994 | 2981 | 2991 | 2995 | 3000 | | CH3 stretching, symmetric | 2837 | 2834 | 2830 | 2830 | 2830 | 2830 | | NH. stretching | Overlapped | — | — | — | — | — | | QS (P), CH deformation, CC stretching (P, BI) | 1629 | 1589 | 1592 | 1592 | 1592 | 1592 | | CH + NH deformation, CC stretching (BI) | 1588 | 1570 | 1572 | 1565 | 1572 | 1572 | | CH + NH deformation (BI) | 1514 | — | — | — | — | — | | SCS (P), CH3 deformation symmetric | 1432 | 1450 | 1454 | 1450 | 1450 | 1446 | | NH + C4H + C5H deformation (BI) | 1356 | — | — | — | — | — | | CH deformation (BI) | — | 1364 | 1364 | 1364 | 1364 | 1364 | | NH + CH deformation symmetric (BI) | 1273 | — | — | — | — | — | | CH deformation (BI) | — | 1274 | 1273 | 1270 | 1272 | 1273 | | NH + CH deformation symmetric (BI) | 1255 | — | — | — | — | — | | CH deformation (BI) | — | 1230 | 1242 | 1241 | 1253 | 1243 | | NH + CH deformation symmetric (BI) | 1232 | — | — | — | — | — | | CH deformation (BI) | — | 1190 | 1225 | 1229 | 1231 | 1229 | | NH + CH deformation symmetric (BI) | 1203 | — | — | — | — | — | | CH deformation (BI) | — | — | 1206 | 1201 | 1211 | 1203 | | NH + CH deformation symmetric (BI) | 1190 | — | — | — | — | — | | S=O stretching vibration | 1009 | 992 | 985 | 1006 | 1002 | 990 | | CH deformation (BI) | 963 | 954 | 954 | 954 | 954 | 954 | | S-C stretching | 653 | 650 | 655 | 644 | 644 | 649 | | 635 | 628 | 623 | 620 | 620 | 620 |
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