Research Article
Spectroscopic Characterization of Omeprazole and Its Salts
Table 4
Assignment of characteristic vibrations in infrared spectra of OMP and its salts.
| | Vibration | OMP | OMP-Li | OMP-Na | OMP-K | OMP-Mg | OMP-Ca |
| | O-H, stretching, H-bonded | — | 3416 | 3434 | 3316 | 3543 | 3406 | | 3241 | 3109 | 3156 | | O-H stretching, free | — | — | — | 3600 | — | — | | CH, stretching (BI, P) | ~3070 | 3063 | 3063 | 3062 | 3063 | 3063 | | CH3 (M), stretching | 2944 | 2935 | 2930 | 2947 | 2930 | 2947 | | NH, stretching | ~2930 | — | — | — | — | — | | QS (P), CH deformation, CC stretching (P, BI) | 1629 | 1608 | 1613 | 1608 | 1613 | 1613 | | CH + NH deformation, CC stretching (BI) | 1587 | — | — | — | — | — | | CC stretching (BI) | — | 1591 | 1591 | 1591 | 1591 | 1591 | | QS (P), CH deformation, CC stretching (P, BI) | 1568 | 1571 | 1570 | 1566 | 1571 | 1571 | | CH + NH deformation (BI) | 1512 | — | — | — | — | — | | SCS (P), CH (B), NH deformation, N3C2 stretching | 1470 (shift) | 1477 | 1477 | 1475 | 1477 | 1477 | | NH + CH deformation (BI), CH deformation (P) | 1410 | — | — | — | — | — | | CH deformation (P) | — | 1386 | 1384 | 1400 | 1410 | 1396 | | NH + CH deformation symmetric (BI) | 1273 | — | — | — | — | — | | CH deformation (BI) | — | 1270 | 1270 | 1270 | 1270 | 1270 | | NH + CH deformation symmetric (BI) | 1253 | — | — | — | — | — | | CH deformation (BI) | — | 1252 | 1242 | 1242 | 1252 | 1252 | | NH + CH deformation symmetric (BI) | 1231 | — | — | — | — | — | | CH deformation (BI) | — | 1228 | 1225 | 1225 | 1230 | 1224 | | NH + CH deformation symmetric (BI) | 1206 | — | — | — | — | — | | CH deformation (BI) | — | 1200 | 1200 | 1200 | 1200 | 1200 | | NH + CH deformation symmetric (BI) | 1188 | — | — | — | — | — | | S=O stretching vibration | 1014 | 1035 | 1031 | 1031 | 1034 | 1031 | | 1015 | 1008 | — | 1015 | 1023 | | 998 | — | 1003 | 1002 | 1002 | | CH deformation (BI) | 967 | 950 | 950 | 950 | 950 | 950 | | S-C stretching | 631 | 628 | 633 | 630 | 637 | 634 | | 621 | — | — | — | — | — |
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