Research Article
Utilization of a Green Brominating Agent for the Spectrophotometric Determination of Pipazethate HCl in Pure Form and Pharmaceutical Preparations
Table 5
Robustness and ruggedness of the proposed methods.
| Parameters | A | B | C | D | E | 2.0 g mL−1 | 4.0 g mL−1 | 6.0 g mL−1 | 3.0 g mL−1 | 3.0 g mL−1 | Recovery (%) ± RSD%a |
| Robustness | | | | | | No variationb | | | | | | Oxidant () | | | | | | 0.8 mL | | | | | | 1.2 mL | | | | | | Oxidation time | | | | | | 2.0 min | | | | | | 10 min | | | | | | 1,10-Phenanthroline (0.2%) | | | | | | 0.8 mL | | | | | | 1.2 mL | | | | | | Ammonia (1 : 1) | | | | | | 0.8 mL | | | | | | 1.2 mL | | | | | | FAS (5 × 10−3 mol L−1) | | | | | | 1.3 mL | | | | | | 1.7 mL | | | | | | SCN− (1.0 mol L−1) | | | | | | 1.8 mL | | | | | | 2.2 mL | | | | | | Ruggedness | | | | | | Interanalysis’ | | | | | | Interinstruments’ | | | | | |
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Average of three determinations.
bFollowing the general assay procedure conditions.
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