Study of Cellular Uptake of Modified Oligonucleotides by Using Time-Resolved Microspectrofluorimetry and Florescence Imaging

Figure 1

Fluorescence microimages of MCF-7 cells incubated overnight with ATTO-dA₁₅/H₂TMPyP4 complex obtained with different emission filters. (a): H₂TMPyP4 emission (610–680 nm); (b): details of the porphyrin and ATTO 425 emission from the cell nucleus and nucleoli; (c): ATTO-dA₁₅ emission (430–500 nm).

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