Research Article

Beninese Plant Extracts with Antiplasmodial Activity Select New Allele Variants Msp1 and Msp2 in Plasmodium falciparum

Table 1

Msp1 and Msp2 alleles of P. falciparum detected in exposed and unexposed parasites.

GenesAllelic familiesFragment sizes (base pairs) per plant extract treatment
Negative controlDissotis rotundifoliaEhretia cymosaHibiscus surattensisCpE2Cola milleniiArtesunate (positive control)Costus afer

Msp1K1150150150150150100150150
200200200200200150200200
250250250250250200250250
700700700700700250700700
700
Mad20150150150150150150150150
250250250250250250250250
RO33200200200200200200200200
700300300700700300700700
700700700

Msp23D7250250250250250250250250
350350350350350350350350
FC27180150180180180180180180
900180300300300300400300
300900400400900900400
400900900600
800900
900

Values shown in the table represent the different alleles classified according to the length (in base pairs).