Antimalarial Efficacy of Ethanol Extract of Bridelia micrantha Stem Bark against Plasmodium berghei-Infected Mice

Table 3

Effect of the extract during the suppression test on the hematological parameters.

Red blood cells

White blood cells

Treatment

Dosage

RBC

Hb

HCT (%)

MCV (fl)

MCH

MCCH

WBC

LYM

NEU

BASO

EOS

MON

Negative control

1% DMSO

^b

^a

^a

^a

^a

^a

^b

^a

^a

^a

^b

^a

CQ

5 mg/kg

^a

^a

^b

^a

^a

^a

^a

^b

^b

^a

^b

^a

Ethanolic extract

150 mg/kg

^a

^a

^a

^a

^a

^a

^a

^c

^c

^a

^b

^a

300 mg/kg

^a

^a

^a

^a

^a

^a

^a

^a

^c

^a

^b

^a

600 mg/kg

^a

^a

^a

^a

^a

^a

^a

^b

^b

^a

^b

^a

Neutral

Distilled H2O

^a

^a

^a

^a

^a

^a

^c

^c

^c

^a

^a

^a

The data are shown as (); values with the same superscript letter do not differ substantially at . Red blood cells are represented by RBC, white blood cells by WBC, hematocrit by HCT, mean corpuscular content in hemoglobin by MCH, and mean corpuscular concentration in hemoglobin by MCCH. MO: leukocytes; BASO: basophils; EOS: eosinophils; NEU: neutrophils; LY: lymphocytes; Hb: hemoglobin.