Research Article
Efficient One-Pot Synthesis of Novel Caffeic Acid Derivatives as Potential Antimalarials
Table 2
The
, , and
values of compounds
1-
6.
| Compound | | | | pH 7.4 | pH 7.2 | pH 5.5 |
| 1 | 2.21 | 9.04 10.40 | 3.39 | 3.39 | 3.40 |
| 2 | 1.34 | 8.82 10.96 14.49 | 2.61 | 2.61 | 2.62 |
| 3 | 1.61 | 8.78 10.90 14.46 | 2.93 | 2.93 | 2.94 |
| 4 | 1.92 | 8.82 10.96 14.49 | 3.10 | 3.10 | 3.11 |
| 5 | 2.63 | 8.32 | 3.60 | 3.62 | 3.65 |
| 6 | 2.97 | 8.35 | 3.78 | 3.79 | 3.82 |
| CA | 0.93 | 3.45 9.28 12.69 | -1.67 | -1.58 | -0.21 |
| CQ | 4.15 | 7.29 10.32 | 0.70 | 0.44 | -1.21 |
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