Journal of Parasitology Research / 2012 / Article / Tab 1 / Review Article
Human Schistosome Infection and Allergic Sensitisation Table 1 Heterogeneity in studies investigating the effect of helminth infection on atopy.
Parasite spp, References Atopy outcome Association Population age Ascaris lumbrocoides [37 ]1 Wheeze, SPT Negative 1–4 years [38 ]2 IgE, PK Negative 5–15 years [39 ]1 SPT, airway responsiveness Positive 8–18 years [40 ]2 Allergen-induced Th2 cytokines None 7–13 years [41 ]2 SPT, wheeze None 9 years mean age [42 ]2 SPT Negative 6–17 years Wheeze, eczema, EIB None Trichuris trichiura [38 ]2 IgE, PK Negative 5–15 years [37 ]1 Wheeze, SPT None 1–4 years [43 ]# SPT Negative 2–8 years Hookworm [37 ]1 Wheeze, SPT None 1–4 years [42 ]2 SPT Negative 6–17 years wheeze, eczema, EIB None Schistosoma mansoni [44 ]1 SPT, IgE Negative
1
8
±
9
.
7
years[45 ]# SPT, asthma symptoms Negative 15 years mean age Schistosoma haematobium [46 ]1 SPT Negative 5–14 years
Cross-sectional 1 and treatment followup 2 studies are reported here.
# Longitudinal approach but treatment intervention was not the primary objective of the study. SPT: skin prick test; PK: Prausnitz-Kustner passive transfer test, EIB: exercise-induced bronchoconstriction.
