In Vitro and In Vivo Quality Evaluation of Glibenclamide Tablets Marketed in Addis Ababa, Ethiopia

Table 2

Results of hardness, friability, disintegration tests, and chemical assay of different brands of glibenclamide tablets included in the study.

Drug Product	Brand	Hardness (N) ±SD	Friability (%)	Disintegration time ±SD (Min)	Assay (%W/W ±SD)
Glibenclamide 5 mg	Betanase	65.83±6.79	0.224	2.83±0.25	101.05±0.16
	Daonil	81.66±4.5	0.106	1.43±0.14	95.53±0.54
	Glamide	50.3±2.65	0.289	1.36±0.09	100.68±1.83
	Glitisol	85.5±3.39	0.105	6.44±0.44	104.33±0.04
	Melix	101.66±3.38	0.126	2.29±0.19	97.32±0.65