Research Article
In Vitro and In Vivo Quality Evaluation of Glibenclamide Tablets Marketed in Addis Ababa, Ethiopia
Table 2
Results of hardness, friability, disintegration tests, and chemical assay of different brands of glibenclamide tablets included in the study.
| Drug Product | Brand | Hardness (N) ±SD | Friability (%) | Disintegration time ±SD (Min) | Assay (%W/W ±SD) |
| Glibenclamide 5 mg | Betanase | 65.83±6.79 | 0.224 | 2.83±0.25 | 101.05±0.16 | Daonil | 81.66±4.5 | 0.106 | 1.43±0.14 | 95.53±0.54 | Glamide | 50.3±2.65 | 0.289 | 1.36±0.09 | 100.68±1.83 | Glitisol | 85.5±3.39 | 0.105 | 6.44±0.44 | 104.33±0.04 | Melix | 101.66±3.38 | 0.126 | 2.29±0.19 | 97.32±0.65 |
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