Research Article
Antidiarrheal and Antioxidant Activities of Methanol Extract of Bryophyllum pinnatum Leaf Harvested from South-Eastern Nigeria in Mice
Table 1
Effect of BPE and loperamide on castor oil induced diarrhea on mice.
| Percentage (%) wet stool | Treatment | 1 h | 2 h | 3 h | 4 h |
| Distilled water 10 ml/kg | 76.66 ± 2.35 | 81.38 ± 2.00 | 82.57 ± 2.27 | 84.62 ± 2.23 | Loperamide 5 mg/kg | 0.00 ± 0.00 | 40.00 ± 16.32 | 88.75 ± 3.39 | 90.00 ± 2.98 | BPE 50 mg/kg | 48.33 ± 9.06 | 63.54 ± 11.01 | 83.06 ± 2.01 | 83.61 ± 2.18 | BPE 100 mg/kg | 28.33 ± 9.77 | 50.00 ± 11.57 | 61.66 ± 8.48 | 72.14 ± 5.13 | BPE 200 mg/kg | 20.83 ± 10.75 | 61.11 ± 2.02 | 63.49 ± 2.89 | 62.50 ± 4.56 |
|
|
when compared with distilled water treated group. BPE = Bryophyllum pinnatum Extract. |