Association of PLGA Microspheres to Carrier Pellets by Fluid Bed Coating: A Novel Approach towards Improving the Flowability of Microparticles

Table 2

Total coated surface values as a function of polymer type, concentration, and ratio.

#	Factors			Total coated surface (%)
	(A) Polymer type	(B) Polymer concentration; (% w/v)	(C) Coating suspension to pellets ratio; (mL/g)
1	Kollidon® VA64	2.5	1:1	26.3
2	Kollidon® VA64	2.5	2:1	65.4
3	Kollidon® VA64	1.0	1:1	26.8
4	Kollidon® VA64	5.0	3:1	82.9
5	Kollicoat® Protect	2.5	2:1	86.9
6	Kollicoat® Protect	2.5	1:1	30.3
7	Kollidon® VA64	5.0	1:1	20.0
8	Kollicoat® Protect	5.0	1:1	26.1
9	Kollidon® VA64	2.5	2:1	63.1
10	Kollicoat® Protect	5.0	2:1	55.7
11	Kollicoat® Protect	2.5	2:1	85.2
12	Kollicoat® Protect	1.0	2:1	88.2
13	Kollidon® VA64	1.0	3:1	93.3
14	Kollidon® VA64	5.0	2:1	51.2
15	Kollicoat® Protect	1.0	3:1	99.1
16	Kollicoat® Protect	2.5	3:1	90.1
17	Kollidon® VA64	1.0	2:1	90.7
18	Kollicoat® Protect	1.0	1:1	27.9
19	Kollicoat® Protect	5.0	3:1	91.0
20	Kollidon® VA64	2.5	3:1	74.7