Research Article
Cocoa Pod Husk Pectin Intended as a Pharmaceutical Excipient Has No Adverse Effects on Haematological Parameters in Sprague Dawley Rats
Table 7
The influence of CPH pectin administration on the platelet indices for female rats.
| | Platelet indices | Day | Control | Low dose
0.714 mg/kg | Medium dose
7.14 mg/kg | High dose
71.4 mg/kg |
| PLT
(x103/ul) | 30 | 1046.30±42.90 | 1096.70±45.60 | 1046.50±53.20 | 1070.00±42.30 | | 60 | 981.30±49.90 | 1033.20±51.00 | 1081.00±61.00 | 942.80±32.40 | | 90 | 1097.00±73.80 | 1048.70±55.20 | 975.50±54.80 | 959.80±20.20 |
| | PDW (fl) | 30 | 8.30±0.12 | 8.62±0.17 | 8.57±0.11 | 8.65±0.09 | | 60 | 8.48±0.08 | 8.57±0.24 | 8.65±0.23 | 8.48±0.15 | | 90 | 8.37±0.14 | 8.27±0.03 | 8.50±0.10 | 8.33±0.11 |
| | MPV (fl) | 30 | 7.00±0.07 | 7.10±0.05 | 7.10±0.09 | 7.18±0.08 | | 60 | 7.07±0.07 | 7.20±0.17 | 7.12±0.14 | 7.05±0.06 | | 90 | 7.07±0.09 | 6.98±0.05 | 7.10±0.10 | 7.02±0.10 |
| | P-LCR (%) | 30 | 6.73±0.30 | 7.08±0.24 | 7.18±0.31 | 7.93±0.55 | | 60 | 7.23±0.37 | 7.25±0.34 | 7.60±0.57 | 7.70±0.20 | | 90 | 7.37±0.33 | 5.95±0.19 | 6.38±0.32 | 6.53±0.43 |
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