Cocoa Pod Husk Pectin Intended as a Pharmaceutical Excipient Has No Adverse Effects on Haematological Parameters in Sprague Dawley Rats

Table 2

Results showing the effect of CPH pectin on red blood cell indices of male rats.

Red blood cell indices	Day	Control	Low dose; 0.714 mg/kg	Medium dose; 7.14 mg/kg	High dose; 71.4 mg/kg
RBC (x 10^6/ul)	30	8.72±0.09	9.16±0.23	8.93±0.14	8.91±0.13
	60	8.78±0.07	8.68±0.12	8.58±0.18	8.60±0.11
	90	9.03±0.11	8.90±0.12	8.77±0.15	8.91±0.14
HGB (g/dl)	30	15.00±0.18	15.52±0.36	15.63±0.43	15.48±0.16
	60	15.37±0.20	15.18±0.34	15.03±0.22	15.08±0.12
	90	15.50±0.13	15.38±0.34	15.35±0.27	15.35±0.18
HCT (%)	30	49.47±0.59	49.68±0.68	49.87±1.07	48.52±0.61
	60	47.48±0.67	47.10±1.21	45.87±0.83	46.88±0.68
	90	48.82±0.44	49.97±0.97	47.62±0.88	50.30±0.78
MCV (fl)	30	55.60±0.19	54.92±0.62	52.95±0.26	53.73±0.35
	60	53.20±0.31	52.65±0.57	53.50±0.36	54.23±0.40
	90	54.08±0.70	53.50±1.11	54.83±0.53	55.88±0.49
MCH (pg)	30	17.08±0.18	16.93±0.26	16.98±0.22	17.15±0.13
	60	17.32±0.11	17.10±0.26	17.52±0.16	17.55±0.12
	90	17.05±0.11	16.92±0.21	17.47±0.39	17.47±0.11
MCHC (g/dl)	30	30.63±0.25	30.53±0.18	31.90±0.19	31.63±0.12
	60	32.37±0.13	32.23±0.19	32.80±0.16	32.18±0.29
	90	31.83±0.12	31.22±0.59	31.60±0.85	30.90±0.18
RDW-SD (fl)	30	29.55±0.26	29.55±0.30	28.00±0.39	27.75±0.40
	60	27.50±0.24	27.03±0.27	27.52±0.07	27.68±0.31
	90	28.55±0.91	29.87±1.28	28.23±0.76	29.83±0.45
RDW-CV (%)	30	13.55±0.56	14.70±0.77	14.57±0.38	12.53±0.39
	60	13.03±0.63	13.08±0.58	13.12±0.33	13.03±0.36
	90	14.30±1.14	15.33±1.40	13.57±0.57	13.58±0.50

Significantly different ( < 0.01)