Biodegradable Polymersomes for the Delivery of Gemcitabine to Panc-1 Cells

Figure 4

PolyGem internalization by Panc-1 cells. (a) Fluorescence intensity of PZn₃-polymersomes internalized by cells in well plates corresponding to 48 hour time point. (b) Concentration of PZn₃ uptake as a function of solution PZn₃ concentration (𝑛=3). Error bars indicate standard deviation. (c) CLSM 𝑧-stack images of Panc-1 cells incubated with PZn₃-polymersomes for 12 hours. Z-slices (Δ𝑧=3 μm) are presented from left to right. Scale bar = 50 μm.

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