Evaluating Antiplasmodial and Antimalarial Activities of Soybean (Glycine max) Seed Extracts on P. falciparum Parasite Cultures and P. berghei-Infected Mice

Table 5

In vivo antimalarial activities of crude extract of Glycine max in prophylactic test on day 4 postparasite exposure and animal survival time.

Treatment	Dose (mg/kg)	Mean ± SD parasitemia (%)	% suppression of parasite	Mean survival time (days)
Peptide extract	200	6.35 ± 0.22	43.14	7.50 ± 0.58
	400	4.78 ± 0.30	57.12	9.25 ± 0.96
	800	3.94 ± 0.46	64.66	10.25 ± 0.96
CQ		1.89 ± 0.16	83.09	28.25 ± 1.50
Vehicle (3% dimethyl sulfoxide and 10% Tween 80 in PBS)		11.16 ± 1.15		5.00 ± 0.82

The results are expressed as mean ± SD.