Sesamol: A Natural Phenolic Compound with Promising Anticandidal Potential

Figure 6

Effect of Ses on membrane composition. (a) UV spectrophotometric sterol profile of C. albicans scanned between 220 and 300 nm from a culture grown for 16 hours with and without Ses (0.552 mg/mL). (b) Relative percentages of ergosterol content in the absence (control) and presence of Ses (0.552 mg/mL). Mean of % ergosterol levels is calculated as described in Section 2 normalized by considering the untreated control as 100 (absolute value of 0.003) ± SD of three independent sets of experiments are depicted on -axis and depicts value < 0.05. (c) Transmission electron micrographic image showing the tampered membrane integrity of C. albicans with or without Ses as described in Section 2.

(a)

(b)

(c)