Congenital Malformations of the Eye: A Pictorial Review and Clinico-Radiological Correlations

Figure 1

Radiological anatomy of the ocular globe. Radiological anatomy of the ocular globe. MRI axial postcontrast T1WI (a), DRIVE (b), T2WI (c), sagittal precontrast T1 (d), and postcontrast T1 (e). The predominant MR signal of the ocular globe is related to aqueous and vitreous humors appearing hyperintense on T2WI/DRIVE (black asterisks in (b)) and hypointense on T1WI (white asterisks in (a) and (e)). The external layer is composed of the sclera and the cornea, appearing hypointense on both T1WI and T2WI (sclera: white arrow in (a) and black arrows in (b); cornea: white arrow in (c)). The middle layer corresponds to the uvea, which is composed of the iris, the ciliary body, and the choroid. The uvea appears hyperintense on T1WI (dotted white arrow in (d)) and hypointense on T2WI. After contrast administration, the uvea, in particular, the choroid (white arrow in (e)) and the ciliary body/iris (dotted white arrow in (a)), present a vivid enhancement. The inner layer corresponds to the retina, which cannot be told apart from the choroid, as it appears hypointense on T2WI and shows enhancement after contrast administration (white arrow in (e)). Crystalline lens is typically hypointense on T2WI (black arrow in (c)) and hyperintense on T1W (white arrow in (d)).