Inhaled Corticosteroid Exposure and Risk of Cataract in Patients with Asthma and COPD: A Systematic Review and Meta-Analysis

Table 3

Quality and bias risk assessment in included cohort and case-control studies.

Cohort studies	Selection				Comparability	Exposure			Score
	Representativeness of the cohort	Nonexposed cohort	Ascertainment of exposure	Outcome of interest is not present at start of study	Based on design and analysis (smoking, sex)	Assessment of outcome	Was follow-up long enough for outcomes to occur?	Adequacy of follow-up of cohorts
Derby and Maier [38]	+	+	+	+	++	+	+	−	8
Jick et al. [33]	+	+	+	+	++	+	+	+	9
Ernst et al. [34]	+	+	+	+	++	+	+	+	9
Wang et al. [21]	+	+	+	+	+	+	+	−	7
Miller et al. [36]	+	+	+	+	++	+	+	+	9
Sullivan et al. [17]	+	+	+	+	+	+	+	+	8
Daugherty et al. [39]	+	+	+	+	+	+	+	+	8
Flynn et al. [14]	+	+	+	+	++	+	+	+	9
Nath et al. [32]	+	−	−	+	+	+	+	+	6
Barry et al. [11]	+	+	+	−	+	+	+	+	7
Bloechlinger et al. [18]	+	+	+	+	++	+	+	+	9
Price et al. [16]	+	+	+	+	++	+	+	+	9
Case-control studies	Is the case definition adequate?	Representativeness of the cases	Selection of Controls	Definition of Controls	Based on design and analysis (smoking, sex)	Ascertainment of exposure	Same method of ascertainment for cases and controls	Non-Response rate
Smeeth et al. [26]	+	+	+	+	+	−	+	+	7
Garbe et al. [35]	+	+	+	+	+	+	+	+	8

Note. “+” indicates a point. A study can be given a maximum of one point for each item within the “Selection” and “Exposure” categories. A maximum of two points can be given for the “Comparability” category.