Diagnostic Accuracy of Corneal and Epithelial Thickness Map Parameters to Detect Keratoconus and Suspect Keratoconus

Table 3

OCT-based epithelial thickness data in normal, suspect keratoconus, and keratoconus groups.

Epithelial thickness (μm)	Normal				SKC				KC				ANOVA	values
	Mean	SD	Range		Mean	SD	Range		Mean	SD	Range		value	SKC vs. normal	KC vs. normal	KC vs. SKC
Min ET (0_2)	47.57	4.1	33	58	45.74	4.25	38	58	37.26	4.51	30	52	<0.0001	0.097	<0.0001	<0.0001
Avg ET (0_2)	49.66	3.71	38	60	48.47	4.4	41	63	43.71	4.93	36	57	<0.0001	0.486	<0.0001	<0.0001
Max ET (0_2)	51.34	3.88	44	62	50.91	4.61	43	66	50.88	7.5	42	81	0.8813
Min-Max ET (0_2)	−3.77	3.17	−20	−1	−5.16	2.74	−11	−1	−13.62	6.58	−39	−4	<0.0001	0.288	<0.0001	<0.0001
Min ET (2_5)	44.45	3.56	33	54	42.84	3.51	37	55	35.68	4.48	29	48	<0.0001	0.106	<0.0001	<0.0001
Avg Et (2_5)	48.75	3.38	42	60	48.56	3.77	42	59	47.21	5.23	39	63	0.1837
Max ET (2_5)	52.6	4.7	45	69	53.3	5.15	43	69	57.26	8.77	47	94	0.0016	1	0.001	0.016
S-I ET (2_5)	−1.55	3.14	−6	11	0.74	8.38	−9	50	6.62	9.16	−4	48	<0.0001	0.289	<0.0001	0.001
SN-IT ET (2_5)	−0.1	3	−8	14	1.72	3.73	−10	10	9.35	4.7	1	19	<0.0001	0.046	<0.0001	<0.0001
Min-Max (2_5)	−8.15	4.65	−26	−3	−10.47	4.18	−22	−4	−21.59	7.79	−52	−11	<0.0001	0.0004	<0.0001	<0.0001
CET	49.92	3.98	36	60	48.49	4.88	41	63	42.97	5.38	33	55	<0.0001	0.373	<0.0001	<0.0001

Min = minimum; ET = epithelial thickness; Avg = average; Max = maximum; Min-Max = minimum-maximum; S-I = superior-inferior; SN-IT = superonasal-inferotemporal; CET = central epithelial thickness; SKC = suspect keratoconus; KC = keratoconus; SD = standard deviation. Statistically significant values . Values in bold are statistically significant.