Diagnostic Accuracy of Corneal and Epithelial Thickness Map Parameters to Detect Keratoconus and Suspect Keratoconus

Table 2

OCT-based corneal thickness data in normal, suspect keratoconus, and keratoconus groups.

Pachymetry (μm)	Normal				SKC				KC				ANOVA	values
	Mean	SD	Range		Mean	SD	Range		Mean	SD	Range			SKC vs. normal	KC vs. normal	KC vs. SKC
Min CT (0_2)	524.97	60.81	294	645	491.49	30.92	422	546	444.94	54.91	287	527	<0.0001	0.004	<0.0001	<0.0001
Avg CT (0_2)	538.02	44.62	456	655	502.21	31.21	436	560	469.41	52.76	307	559	<0.0001	<0.0001	<0.0001	0.004
Max CT (0_2)	552.89	42.34	480	671	516.91	32.23	452	579	499.94	48.96	344	592	<0.0001	<0.0001	<0.0001	0.227
Min-Max (0_2)	−27.92	44.61	−256	−8	−25.42	10.72	−58	−9	−55.94	20.94	−106	−26	0.0001	0.0015	<0.0001	0.0001
Min CT (2_5)	524.49	63.19	282	644	491.58	30.8	422	546	447.62	49.38	312	527	<0.0001	0.005	<0.0001	0.001
Avg CT (2_5)	556.66	43.25	483	671	523.56	32.28	460	581	510.65	37.27	401	586	<0.0001	<0.0001	<0.0001	0.444
Max CT (2_5)	598.46	45.73	515	718	564.51	36.12	503	655	564.74	32.72	505	623	<0.0001	<0.0001	<0.0001	1
S-I CT (2_5)	6.80	40.07	−214	59	18.7	15.12	−5	76	28.75	24.05	−38	90	0.0041	0.157	0.004	0.482
SN-IT CT (2_5)	19.51	36.12	−179	63	33.49	15.11	−2	80	46.25	24.72	−30	109	0.0001	0.043	<0.0001	0.168
Min-Max CT (2_5)	−73.97	52.32	−345	−39	−72.93	20	−133	−42	−117.12	44.84	−220	7	0.0001	0.0503	0.0001	0.0001
CCT	537.13	43.66	449	652	498.93	31.42	433	558	462.03	55.99	287	554	<0.0001	<0.0001	<0.0001	0.001

Min = minimum; CT = corneal thickness; Avg = average; Max = maximum; Min-Max = minimum-maximum; S-I = superior-inferior; SN-IT = superonasal-inferotemporal; CCT = central corneal thickness; SKC = suspect keratoconus; KC = keratoconus; SD = standard deviation. Statistically significant values . Values in bold are statistically significant.