Research Article

Efficacy of Topical Azithromycin versus Systemic Doxycycline in Treatment of Meibomian Gland Dysfunction

Table 4

Pain and discomfort, lid margin telangiectasia, conjunctivitis, frothy discharge, meniscus floaters and break-up time test in 2nd follow up between studied groups.

Topical azithromycin (n = 28)Systemic doxycycline (n = 28) value

Pain and discomfortMild19 (67.86%)17 (60.71%)0.828
Moderate7 (25.00%)8 (28.57%)
Severe2 (7.14%)3 (10.71%)

Lid margin telangiectasia0 & 113 (46.43%)9 (32.14%)0.452
211 (39.29%)12 (42.86%)
34 (14.29%)7 (25.00%)

Conjunctivitis+ve4 (14.29%)11 (39.29%)0.068
−ve24 (85.71%)17 (60.70%)

Frothy discharge+ve1 (3.57%)3 (10.71%)0.611
−ve27 (96.43%)25 (89.28%)

Meniscus floaters+ve5 (17.86%)13 (46.43%)0.044
−ve23 (82.14%)15 (53.57%)

Break-up time test (seconds)9.11 ± 2.647.71 ± 1.980.029
6–145–11

Data are presented as mean ± SD, : significant as value ≤ 0.05.