Association between Aqueous Humor Cytokines and Structural Characteristics Based on Optical Coherence Tomography in Patients with Diabetic Macular Edema

Table 2

Comparison of aqueous humor cytokine concentrations (pg/ml) and retinal choroidal structural parameters in patients with different types of DME.

	SRD			CME			DRT
	Without (n = 31)	With (n = 9)		Without (n = 8)	With (n = 32)		Without (n = 10)	With (n = 30)
IL-6	4.7 (7–20.8)	35.2 (8.3–45.1)	0.037	12.9 (5.3–66.9)	8.6 (5–34.4)	0.521	5.6 (3.7–11.4)	13.3 (6.1–35.6)	0.042
IL-8	4.1 (6.2–17.7)	15.1 (9.8–36)	0.054	6.4 (3.8–29)	8.7 (4.6–18.9)	0.710	7.9 (3.4–19.3)	8.0 (4.6–20.8)	0.492
IL-10	2.6 (2.5–2.8)	2.9 (2.5–3.6)	0.331	2.8 (2.6–3.1)	2.6 (2.5–2.9)	0.437	2.7 (2.3–2.7)	2.7 (2.5–3.1)	0.200
VEGF	61.4 (26.9–101.2)	110.8 (61.5–135.2)	0.078	33.4 (11.8–51.3)	84 (52.5–130.2)	0.005	62.5 (22.6–97.9)	71.3 (38.2–123.5)	0.399
VCAM-1	1720.5 (737.3–2436.2)	2258 (1278.3–3309.7)	0.169	2340.5 (899.6–4023.1)	1750.6 (746.3–2453.4)	0.295	972.0 (407.8–1974.7)	1829.2 (995.5–2980.3)	0.070
ICAM-1	728.6 (455.6–1079.4)	651.1 (523.7–1222.4)	0.859	749.1 (383.4–1337.7)	699.8 (486.8–1058.8)	0.761	611.1 (139.5–1413.1)	730.4 (566.4–1017.5)	0.333
TGF-β1	19.2 (17–23.6)	26.4 (17.7–46)	0.145	21.9 (17.5–68.1)	19.6 (16.9–24.0)	0.327	17.6 (16.4–21.0)	22.1 (17.3–34.8)	0.039
FGF	6.3 (5.1–7.9)	8.3 (6.2–9.5)	0.048	5.8 (4.5–11)	7.0 (5.2–8.1)	0.565	6.9 (5.5–7.9)	6.4 (4.6–8.2)	0.755
MCP-1	610.9 (434.2–954.4)	717.1 (474.7–939.4)	0.611	767.2 (339.5–863.3)	614.2 (459.2–969.4)	0.684	380.5	642.3	0.014
CMT (μm)	375 (324–517)	495 (372–571)	0.116	331 (292–460)	435 (340–545)	0.073	361 (329–497)	426 (333–530)	0.851
MV (mm^3)	0.29 (0.26–0.41)	0.39 (0.29–0.45)	0.116	0.27 (0.23–0.36)	0.35 (0.27–0.43)	0.081	0.28 (0.26–0.39)	0.34 (0.26–0.42)	0.827
CT (μm)	260.4 ± 60.9	277.6 ± 87.4	0.506	221.5 ± 89.4	275.0 ± 56.9	0.042	258.3 ± 44.5	266.3 ± 73.4	0.749
HRF	9.5 (5.8–13)	15 (13.5–29)	<0.000	9.5 (4.5–12.5)	11 (6–15)	0.402	6 (5–9.5)	13 (9.5–15)	0.004

Bold values: significant p-values (p < 0.05).