Journal of Ophthalmology / 2023 / Article / Tab 2 / Research Article
Association between Aqueous Humor Cytokines and Structural Characteristics Based on Optical Coherence Tomography in Patients with Diabetic Macular Edema Table 2 Comparison of aqueous humor cytokine concentrations (pg/ml) and retinal choroidal structural parameters in patients with different types of DME.
SRD CME DRT Without (n = 31) With (n = 9) Without (n = 8) With (n = 32) Without (n = 10) With (n = 30) IL-6 4.7 (7–20.8) 35.2 (8.3–45.1) 0.037 12.9 (5.3–66.9) 8.6 (5–34.4) 0.521 5.6 (3.7–11.4) 13.3 (6.1–35.6) 0.042 IL-8 4.1 (6.2–17.7) 15.1 (9.8–36) 0.054 6.4 (3.8–29) 8.7 (4.6–18.9) 0.710 7.9 (3.4–19.3) 8.0 (4.6–20.8) 0.492 IL-10 2.6 (2.5–2.8) 2.9 (2.5–3.6) 0.331 2.8 (2.6–3.1) 2.6 (2.5–2.9) 0.437 2.7 (2.3–2.7) 2.7 (2.5–3.1) 0.200 VEGF 61.4 (26.9–101.2) 110.8 (61.5–135.2) 0.078 33.4 (11.8–51.3) 84 (52.5–130.2) 0.005 62.5 (22.6–97.9) 71.3 (38.2–123.5) 0.399 VCAM-1 1720.5 (737.3–2436.2) 2258 (1278.3–3309.7) 0.169 2340.5 (899.6–4023.1) 1750.6 (746.3–2453.4) 0.295 972.0 (407.8–1974.7) 1829.2 (995.5–2980.3) 0.070 ICAM-1 728.6 (455.6–1079.4) 651.1 (523.7–1222.4) 0.859 749.1 (383.4–1337.7) 699.8 (486.8–1058.8) 0.761 611.1 (139.5–1413.1) 730.4 (566.4–1017.5) 0.333 TGF-β 1 19.2 (17–23.6) 26.4 (17.7–46) 0.145 21.9 (17.5–68.1) 19.6 (16.9–24.0) 0.327 17.6 (16.4–21.0) 22.1 (17.3–34.8) 0.039 FGF 6.3 (5.1–7.9) 8.3 (6.2–9.5) 0.048 5.8 (4.5–11) 7.0 (5.2–8.1) 0.565 6.9 (5.5–7.9) 6.4 (4.6–8.2) 0.755 MCP-1 610.9 (434.2–954.4) 717.1 (474.7–939.4) 0.611 767.2 (339.5–863.3) 614.2 (459.2–969.4) 0.684 380.5 642.3 0.014 CMT (μ m) 375 (324–517) 495 (372–571) 0.116 331 (292–460) 435 (340–545) 0.073 361 (329–497) 426 (333–530) 0.851 MV (mm3 ) 0.29 (0.26–0.41) 0.39 (0.29–0.45) 0.116 0.27 (0.23–0.36) 0.35 (0.27–0.43) 0.081 0.28 (0.26–0.39) 0.34 (0.26–0.42) 0.827 CT (μ m) 260.4 ± 60.9 277.6 ± 87.4 0.506 221.5 ± 89.4 275.0 ± 56.9 0.042 258.3 ± 44.5 266.3 ± 73.4 0.749 HRF 9.5 (5.8–13) 15 (13.5–29) <0.000 9.5 (4.5–12.5) 11 (6–15) 0.402 6 (5–9.5) 13 (9.5–15) 0.004
Bold values: significant p-values (p < 0.05).