Clinical Comparison of Fusarium Keratitis according to the Initial Potassium Hydroxide (KOH) Smear: A Retrospective Study in South Korea
Table 7
Risk factor for poor clinical outcomes in the total cohort of patients with culture-provenFusarium keratitis (univariate and multivariate logistic regression analyses).
Variables
Univariate
Multivariate
Odds ratio
95% CI
value
Odds ratio
95% CI
value
Male sex
1.292
0.520–3.212
0.581
Age (≥70 years)
1.362
0.546–3.397
0.507
DM
0.900
0.285–2.843
0.858
Agricultural occupation
0.574
0.213–1.549
0.273
Ocular trauma
0.480
0.187–1.233
0.127
Previous ocular surface disease
2.347
0.687–8.022
0.174
Central corneal lesion
3.987
1.482–10.727
0.006
3.500
1.018–12.040
0.047
Deep stromal infiltration
0.289
0.109–0.772
0.013
—
—
—
Ulcer size ≥ 7.5 mm2
5.672
2.075–15.505
0.001
4.980
1.504–16.490
0.009
Initial BCVA < 0.02 (Snellen)
2.667
1.035–6.873
0.042
—
—
—
Hypopyon
2.252
0.892–5.689
0.086
—
—
—
Endothelial plaque
4.053
0.832–19.749
0.083
7.004
1.189–41.271
0.031
KOH stain positivity
0.424
0.167–1.079
0.072
—
—
—
Bacterial mixed infection
2.308
0.580–9.176
0.235
Admission treatment
4.600
0.831–25.449
0.080
8.227
0.892–75.868
0.063
CI = confidence interval; DM = diabetes mellitus; BCVA = best corrected visual acuity; KOH = potassium hydroxide. Multivariate logistic regression analysis was performed using the backward conditional method for the factors with a value <0.1 in univariate logistic regression analysis.