Research Article

A Critical Assessment of Friedenwald’s Technique for Estimating the Coefficient of Rigidity of the Cornea

Table 1

Distribution of Ko estimations according to results taken by the two operators from keratoconus, post-CXL, and normal controls. The number of Ko values (proportion of total in parenthesis) per Ko range. K-S = Result of Kolmogorov–Smirnov test for normality of data in each column. Indicates where the significance of the K-S statistic was <0.05 after excluding Ko values ≥ 0.11.

Operator 1Operator 2

Ko range (mmHg/μL)KeratoconusPost-CXLNormalKeratoconusPost-CXLNormal
0–0.019 (0.18)7 (0.18)1 (0.05)6 (0.12)9 (0.23)1 (0.05)
0.011–0.0221 (0.41)15 (0.38)9 (0.45)24 (0.47)20 (0.50)10 (0.50)
0.021–0.0314 (0.28)11 (0.28)2 (0.10)11 (0.22)5 (0.25)5 (0.25)
0.031–0.045 (0.10)4 (0.10)4 (0.20)2 (0.04)1 (0.025)1 (0.05)
0.041–0.051 (0.10)2 (0.04)2 (0.05)1 (0.05)
0.051–0.061 (0.02)
0.061–0.07
0.071–0.08
0.081–0.091 (0.02)
0.091–0.10
≥0.112 (0.04)3 (0.08)3 (0.15)4 (0.08)3 (0.075)2 (0.10)
K-S0.2620.3480.1990.3400.2890.387