Structural and Biomechanical Corneal Differences between Type 2 Diabetic and Nondiabetic Patients

Table 4

Multivariate regression analysis of the relative effects of clinical and ocular characteristics on corneal biomechanical parameters: corneal hysteresis (CH) and corneal resistance factor (CRF).

Parameter	CH		CRF
	B (95% CI)		B (95% CI)
Age (y)	−0.001 (−0.04 to +0.03)	0.965	−0.003 (−0.04 to +0.04)	0.879
Gender (male)	−0.24 (−0.64 to +0.17)	0.250	−0.303 (−0.80 to +0.19)	0.231
CCT (μm)	+0.02 (+0.01 to +0.02)	<0.001	+0.02 (+0.01 to +0.03)	<0.001
IOPcc (mmHg)	−0.21 (−0.27 to −0.15)	<0.001	+0.09 (+0.02 to +0.16)	0.014
DM duration
Non-DM	—	—	—	—
DM2 < 10 y	−0.06 (−0.53 to +0.41)	0.792	−0.08 (−0.66 to +0.50)	0.792
DM2 ≥ 10 y	+0.411 (−0.05 to +0.87)	0.080	+0.48 (−0.08 to +1.05)	0.093

Data were derived from generalized linear models. represents statistical significance. CH, corneal hysteresis; CI, confidence interval; CRF, corneal resistance factor; D, diopters; DM, diabetes mellitus; mm, millimeters; y, years; μm, micrometer. The remaining variables (HbA1c, smoking history, BMI, AL, Km, and IOP-GAT) did not influence the model and were excluded.