Research Article

Six-Year Real-World Outcomes of Antivascular Endothelial Growth Factor Monotherapy and Combination Therapy for Various Subtypes of Polypoidal Choroidal Vasculopathy

Table 1

Baseline characteristics of the participants with various subtypes of polypoidal choroidal vasculopathy.

Subtype 1Subtype 2

Patients (n)2423
Gender (n), female/male8/1610/130.556
Age (year), mean ± SD64.3 ± 7.661.3 ± 8.00.184
Best-corrected visual acuity (logMAR), mean ± SD0.54 ± 0.360.55 ± 0.370.965
Optical coherence tomography features
 Continuous external limiting membrane (n)230.666
 Continuous ellipsoid zone (n)020.234
 Continuous retinal pigment epithelium (n)6170.001
 Intraretinal fluid (n)15110.375
 Subretinal fluid (n)11180.036
Indocyanine green angiography features
 Greatest linear dimension (μm), mean ± SD3859.7 ± 1625.61862.0 ± 1011.0<0.001
 The distance from foveola to the nearest polyp (μm), mean ± SD1897.2 ± 1126.4655.5 ± 540.7<0.001
 The distance from foveola to branching vascular network (μm), mean ± SD255.1 ± 497.4340.7 ± 433.20.551
 Configuration of polyps (n), isolated/interconnected7/1718/50.001
 Number of polyps (n), single/multiple1/2311/120.001
 Treatment regimen (n), anti-VEGF monotherapy/combination therapy11/1313/100.564

logMAR, logarithm of minimum angle of resolution; SD, standard deviation; VEGF, vascular endothelial growth factor.