Effect of Collagen Cross-Linking on Alkali Burn-Induced Corneal Neovascularization in Rabbits

Table 1

CNV area at different time points.

Group	The CNV area（ ± s, mm^2）
	n	4 days	7 days	10 days	14 days
Group A (alkali burns with treatment)	5	23.24 ± 2.13	69.38 ± 10.01	90.19 ± 4.21	119.22 ± 14.58
Group B (alkali burns with 30 min CXL)	5	20.89 ± 4.99	57.07 ± 9.30	84.17 ± 4.77	111.47 ± 9.84^#
Group C (alkali burns with 15 min CXL)	5	20.19 ± 4.84	55.30 ± 9.44	79.67 ± 10.55	104.56 ± 27.77
Group D (alkali burns with 45 min CXL)	5	19.77 ± 3.78	53.68 ± 11.98	70.70 ± 7.75	86.33 ± 6.22
Group E (alkali burns 1 day later with 30 min CXL)	5	21.94 ± 5.80	57.19 ± 9.69	70.47 ± 16.06	103.71 ± 9.95
Group F (alkali burns 3 day later with 30 min CXL)	5	19.43 ± 2.74	58.94 ± 8.10	84.11 ± 14.25	109.94 ± 4.01^#
Two-way repeated measures ANOVA (F, )
Groups	5.515, <0.002
Time points	545.48, <0.000
Groups ∗ time points	1.485, 0.134

LSD-t test was used for pairwise comparison, with significant mark : Comparison with group A. Comparison with group D.