Nonsurgical Procedures for Keratoconus Management

Table 2

Description of the main studies in keratoconus (KC) management with soft contact lenses (SCLs).

Author	Type of study	Type CL	Sample size (eyes)	Severity KC (number of cases)	Follow-up (months) (mean)	Mean age (years)	Sex (female/male)	HOA (μm)	UCVA (logMAR) (mean)	BCLCVA (logMAR) (mean)
Gumus and Kahraman [16]	Prospective comparative	SCL SiH (Toris K)	50/20/30†	Moderate (50)	2 Weeks	24.5	32/18	0.710.49†	NR	0.00
Fernandez-Velazquez [20]	Retrospective	SCL SiH (KeraSoft IC)	94	Mild (22); Moderate (46); Severe (6)	10.3	35.5	NR	NR	NR	0.04
Suzaki et al. [26]	Prospective cases series	SCL SiH	30	Moderate (30)	NR	34.7	6/24	0.56	NR	−0.11
Sultan et al. [13]	Retrospective	SCL SiH (Toris K)	64	Mild-moderate (46); Severe (10)	11.94	27.92	26/24	NR	0.83	0.20
Yildiz et al. [17]	Prospective case series	SCL SiH	24	Mild (6); Moderate (13); Severe (5)	4	31.7	4/8	NR	NR	0.10
Yilmaz et al. [19]	Retrospective	SCL SiH	60	Moderate (60)	24	27.3	18/23	NR	0.85	0.16

UCVA: uncorrected visual acuity; BCLCVA: best contact lens corrected visual acuity; HOA: high order aberration; CLIQ: contact lens impact on quality of life questionnaire; CXL: corneal cross-linking; NR: not reported. Mild KC (average sim K < 45 D); moderate (average sim K 45–52 D); severe (average sim K > 52 D). No previous CXL. ^†Previous CXL.