iStent® Trabecular Microbypass Stent: An Update

Table 2

Summary of iStent case series.

Authors (year)		Procedure	Device	Mean IOP reduction (%)	Medication reduction (%)	Follow-up; (months)
Spiegel et al. [7]^1 (2007)	6	1 iStent	iStent	23.9	18.5	12
Buchacra et al. [20]^1 (2011)	10	1 iStent	iStent	27.3	62.0	12
Ahmed et al. [21]^1 (2014)	39	2 iStents + travoprost	iStent	46.9	50	18
Voskanyan et al. [31]^1 (2014)	99	2 iStents	iStent inject	39.7	N/A	12
Arriola-Villalobos et al. [30]^1 (2013)	20	Phaco.  +  1 iStent or 2 iStents	iStent inject	35.7	76.9	12
Spiegel et al. [13]^1 (2008)	47	Phaco. + 1 iStent	iStent	25.4	66.7	6
Spiegel et al. [12]^1 (2009)	47	Phaco. + 1 iStent	iStent	21.4	75.0	12
Arriola-Villalobos et al. [16]^1 (2012)	19	Phaco. + 1 iStent	iStent	16.3	63.6	60
Patel et al. [14]^1 (2013)	44	Phaco. + 1 iStent	iStent	20.9	74.3	6
Belovay et al. [22]^1 (2012)	53	Phaco. + iStents (2 or 3)	iStent	20.2–20.4	64.3–84.6	12
Klamann et al. [32]^2 (2015)	35	1 iStent in phakic OAG	iStent inject	33–35	N/A^3	6
El Wardani et al. [34]^2 (2015)	131	Phaco. alone and 1 iStent or 2 iStents	iStent	N/A^4	27^5	6

IOP, intraocular pressure; , number of eyes enrolled; Phaco., phacoemulsification; OAG, open-angle glaucoma.
The numerical value listed under “medication reduction” represents the decrease in mean number of IOP lowering medications used postoperatively.
¹Prospective studies.
²Retrospective studies.
³No statically significant difference was found at the end of follow-up.
⁴Percentage of reduction was not available in abstract (epub ahead of printing).
⁵Number of medications was reduced by 8% in the phacoemulsification alone group, 27% when using one iStent, and 45% when using 2 iStents.