Clinical Study

Evaluation of Intrastromal Riboflavin Concentration in Human Corneas after Three Corneal Cross-Linking Imbibition Procedures: A Pilot Study

Figure 1

Scatter plot showing intrastromal riboflavin concentration (mcg/dg) per individual data in each group (EpiOff, EpiOff-RICROLIN+, EpiOn-RICROLIN+, and iontophoresis RICROLIN+). The pilot study results confirm that iontophoresis-assisted riboflavin imbibition reaches higher riboflavin intrastromal concentrations compared to EpiOn technique, but still the efficacy of riboflavin imbibition is inferior to EpiOff standard technique.