Research Article
A Case-Control Study of the Association of Leptin Gene Polymorphisms with Plasma Leptin Levels and Obesity in the Kerala Population
Table 3
Adiposity measures and serum leptin level of subjects with LEP SNPs.
| SNPs | ID No. | Genotype | Age/sex | BMI (kg/m2) | WHR | BF (%) | Leptin (ng/ml) | Family history of obesity |
| rs570757178 | C063 | CG | 36/F | 23.3 | 0.91 | 33.8 | 27.1 | No | C155 | CG | 41/M | 23.4 | 1.03 | 29.8 | 4.36 | No | P288 | CG | 38/M | 27.6 | 0.93 | 22.5 | 19.7 | No | P291 | CG | 40/M | 26.3 | 1.01 | 28.1 | 7.41 | No |
| rs6976701 | P055 | AG | 35/M | 28.6 | 1.04 | 27.3 | 40.7 | No | P203 | AG | 35/M | 25.1 | 0.91 | 21.6 | 20.6 | No | P286 | AG | 43/M | 28 | 0.92 | 26.4 | 15.9 | Yes (both parents) | P288 | AG | 27/M | 27.6 | 0.93 | 22.5 | 19.7 | Yes (both parents) | P289 | AG | 51/M | 35.4 | 0.96 | 36.9 | 25.6 | No | P292 | AA | 29/M | 25.2 | 0.92 | 27.8 | 13.2 | Yes (both parents) |
| rs142904532 Thr 5 Thr | P184 | CG | 54/M | 44.8 | 1.0 | 54 | 137 | Yes (both parents) |
| rs201067336 Phe 17 Leu | P169 | GT | 39/F | 27.9 | 0.9 | 42 | 89.3 | No | P202 | GT | 26/M | 25.2 | 0.9 | 23 | 1.8 | No |
| rs111650508 Lys36Arg | P171 | AG | 51/M | 26.9 | 1.0 | 32 | 6.6 | Yes (mother) |
| rs28954114 | P076 | GA | 25/F | 27.3 | 0.92 | 35.9 | 46.4 | Yes (mother) | C145 | GA | 37/F | 17.5 | 0.82 | 28.6 | 5.01 | No | C248 | GA | 22/M | 16.8 | 0.95 | 9.55 | 2.0 | No |
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Study subjects identification number is given with “C” or “P” as prefix. “C” represents control and “P” case (people with obesity).
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