Research Article
Association of Obesity with Proteasomal Gene Polymorphisms in Children
Table 3
Genotype frequencies in the obese case group (
) and non-obese control group (
).
| Gene | SNP | Genotyping results | Genotype | Subjects () | Frequency (%) | Significance values | Case | Control | Case | Control | | CI 95% |
| PSMA6 | c.-110C>A | CC | 83 | 166 | 88.3 | 86.9 | 0.74 | 0.43–1.85 | CA | 11 | 25 | 11.7 | 13.1 | AA | 0 | 0 | 0 | 0 | c.-8C>G | CC | 78 | 158 | 83.0 | 82.7 | 0.43 | 0.59–1.97 | CG | 14 | 32 | 14.9 | 16.8 | GG | 2 | 1 | 2.1 | 0.5 | PSMA3 | c. 543+138G>A | GG | 35 | 102 | 37.2 | 53.4 | 0.0008 | 0.85–1.8 | GA | 54 | 66 | 57.5 | 34.6 | AA | 5 | 23 | 5.3 | 12.0 |
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SNP: single nucleotide polymorphism. value based on method and 10,000 permutations. CI 95% indicates confidence interval.
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