Significance of SUV Max for Predicting Occult Lymph Node Metastasis and Prognosis in Early-Stage Tongue Squamous Cell Carcinoma

Table 3

Univariate and multivariate Cox model analyses of risk factors for the locoregional control survival in patients with cT1-2N0 tongue squamous cell carcinoma.

Variables	Univariate		Cox model
		HR (95% CI)		HR (95% CI)
Age (<40 vs. ≥40)	0.621	1.395 (0.684–3.678)
Gender	0.463	2.003 (0.771–6.874)
Smoking	0.555	2.224 (0.412–8.663)
Drinking	0.746	1.228 (0.229–9.007)
SUV max (≤9.7 vs. >9.7)	0.045	3.445 (1.223–8.247)	0.034	2.472 (1.445–4.752)
Pathologic tumor stage (T1 vs. T2)	0.022	5.221 (1.888–12.521)	0.568	4.612 (0.741–9.667)
Pathologic neck lymph node stage (N0 vs. N+)	0.004	6.221 (1.997–15.322)	<0.001	4.668 (1.964–9.972)
Perineural invasion	0.069	2.665 (0.975–6.335)
Extracapsular extension	0.785	3.556 (0.639–8.554)
Lymphovascular invasion	0.042	2.334 (1.547–7.338)	0.031	2.558 (1.487–5.221)
Tumor differentiation	0.011	4.557 (2.006–13.332)
Well
Moderate			0.152	2.667 (0.856–6.442)
Poor			0.006	3.978 (1.997–9.331)
Radiotherapy	0.641	0.885 (0.437–3.669)