Urotensin-II-Targeted Liposomes as a New Drug Delivery System towards Prostate and Colon Cancer Cells

Table 3

IC₅₀ values after 72 h treatment with free doxo, doxo encapsulated in liposomes (Lipo-doxo), and doxo encapsulated in liposomes conjugated with UT-II (LipoUT-doxo).

Cell lines	Doxo (IC50μm)	Lipo-doxo (IC50μm)	LipoUT-doxo (IC50μm)	UTR expression
DU145	0.6 ± 0.016	2 ± 0.013	15 ± 0.076	Low
PC3	4 ± 0.031	5 ± 0.018	18 ± 0.089	High
LNCaP	1 ± 0.011	>20 ± 0.091	10 ± 0.045	High
WIDR	0.6 ± 0.018	10 ± 0.087	2.5 ± 0.018	High
LoVo	1.25 ± 0.013	7 ± 0.064	5 ± 0.013	Low