Urotensin-II-Targeted Liposomes as a New Drug Delivery System towards Prostate and Colon Cancer Cells

Figure 3

(a) Confocal microscopy images of DU145 and PC3 after 6 h of incubation at 37°C with fluorescent-labeled liposomes. Representative images of control, unconjugated liposomes (Lipo-Bodipy), and liposomes conjugated with UT-II (LipoUT-Bodipy). For each cell line, images on the left panel report that the red fluorescence associated with the Ab against vimentin; images on the right panel report the green fluorescence associated with Bodipy. The cells were visualized with a confocal microscope at magnification 100x. (b) Quantification of fluorescence intensity was reported as arbitrary units. The experiments were performed at least three times, and the results were always similar. Bars, SDs. .

(a)

(b)