Polymorphisms in Survivin (BIRC5 Gene) Are Associated with Age of Onset in Breast Cancer Patients

Table 1

Patient clinicopathological characteristics.

Characteristic	No. of patients (%)
Age at diagnosis (years)
< 40	1 (3.8)
40-50	9 (34.6)
50-60	8 (30.8)
> 60	8 (30.8)
Years since operation
5	8 (30.8)
10	15 (57.7)
15	3 (11.5)
Histological grade
1	4 (14.8)
2	12 (44.4)
3	10 (37.0)
N.A	1 (3.7)
Tumour size
1 (≤ 2 cm)	20 (74.1)
2 (> 2 ≤ 5 cm)	6 (22.2)
3 (> 5 cm)	1 (3.7)
Oestrogen receptor status
Positive	21 (77.8)
Negative	6 (22.2)
Progesterone receptor status
Positive	16 (59.3)
Negative	11 (40.7
Her2 status
Positive	2 (7.4)
Negative	22 (81.5)
N.A.	3 (11.1)
Lymph node status
Positive	11 (40.7)
Negative	16 (59.3)
Pathologic Characteristics
Invasive ductal carcinoma	22 (81.5)
Medullary carcinoma	2 (7.4)
Invasive lobular carcinoma	1 (3.7)
Mixed invasive ductal/lobular carcinoma	1 (3.7)
Papillary carcinoma	1 (3.7)
Ki67 status
Positive	12 (44.4)
Negative	12 (44.4)
N.A.	3 (11.1)

Patient data not available.