Journal of Nutrition and Metabolism

Developmental Origins of Health and Disease


Publishing date
01 Jun 2012
Status
Published
Submission deadline
01 Dec 2011

1School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK

2University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA

3Liggins Institute, The University of Auckland, Private Bag 92019, Victoria Street West, Auckland 1142, New Zealand


Developmental Origins of Health and Disease

Description

Risk of chronic disease during adulthood is partly determined by early life experience. A robust body of epidemiological evidence shows that fetal exposure to maternal undernutrition, or maternal obesity, is associated with greater risk of coronary heart disease, type 2 diabetes, chronic renal disease, and a range of other conditions associated with ageing. The biological plausibility of this nutritional programming has been demonstrated by experiments in which the diet is manipulated during pregnancy in a wide range of animal species.

We invite investigators to contribute original research articles and review articles that will stimulate continuing efforts to understand the basis of nutritional programming. We are interested in articles which report findings from relevant retrospective and prospective human cohorts, or which offer observations from experiments using both established and novel animal models of programming. Articles which add to understanding of the molecular mechanisms which explain the relationships between nutritional status in early life and long-term risk of disease will be of particular relevance to this call. Potential topics include, but are not limited to:

  • Studies of maternal nutritional status during pregnancy in relation to birth outcomes and later health
  • Mechanisms which underpin nutritional programming of health and disease
  • Advances in understanding how the nutritional environment regulates the epigenome
  • Programming and maternal obesity
  • Programming and cancer
  • Paternal influences on fetal development
  • Gender differences in programming mechanisms and phenotypic outcomes
  • Interventions which reverse intrauterine programming
  • Identification of novel biomarkers which predict long-term programming
  • Influences of infant nutrition in the first year of life upon later health and disease

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jnume/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 838640
  • - Editorial

Developmental Origins of Health and Disease

Simon C. Langley-Evans | Barbara Alexander | ... | Deborah M. Sloboda
  • Special Issue
  • - Volume 2012
  • - Article ID 632548
  • - Review Article

Fetal Programming of Body Composition, Obesity, and Metabolic Function: The Role of Intrauterine Stress and Stress Biology

Sonja Entringer | Claudia Buss | ... | Pathik D. Wadhwa
  • Special Issue
  • - Volume 2012
  • - Article ID 431574
  • - Research Article

Neonatal SSRI Exposure Programs a Hypermetabolic State in Adult Mice

Gary J. Kummet | Sarah E. Haskell | ... | Robert D. Roghair
  • Special Issue
  • - Volume 2012
  • - Article ID 930364
  • - Research Article

Maternal Hyperglycemia Disrupts Histone 3 Lysine 36 Trimethylation of the IGF-1 Gene

Erin K. Zinkhan | Qi Fu | ... | Robert H. Lane
  • Special Issue
  • - Volume 2012
  • - Article ID 296935
  • - Research Article

The Effect of Neonatal Leptin Antagonism in Male Rat Offspring Is Dependent upon the Interaction between Prior Maternal Nutritional Status and Post-Weaning Diet

J. Beltrand | D. M. Sloboda | ... | M. H. Vickers
  • Special Issue
  • - Volume 2012
  • - Article ID 837901
  • - Review Article

The Interplay between Estrogen and Fetal Adrenal Cortex

Jovana Kaludjerovic | Wendy E. Ward
  • Special Issue
  • - Volume 2012
  • - Article ID 989037
  • - Research Article

Mitochondrial Respiration Is Decreased in Rat Kidney Following Fetal Exposure to a Maternal Low-Protein Diet

Sarah Engeham | Kennedy Mdaki | ... | Simon C. Langley-Evans
  • Special Issue
  • - Volume 2012
  • - Article ID 397389
  • - Research Article

The Effects of Prenatal Protein Restriction on -Adrenergic Signalling of the Adult Rat Heart during Ischaemia Reperfusion

Kevin J. P. Ryan | Matthew J. Elmes | Simon C. Langley-Evans
  • Special Issue
  • - Volume 2012
  • - Article ID 930591
  • - Review Article

Antenatal Corticosteroids: A Risk Factor for the Development of Chronic Disease

Elizabeth Asztalos
  • Special Issue
  • - Volume 2012
  • - Article ID 158643
  • - Research Article

Relation of Growth Rate from Birth to Three Months and Four to Six Months to Body Mass Index at Ages Four to Six Years

Robert J. Karp | Tawana Winkfield-Royster | Jeremy Weedon
Journal of Nutrition and Metabolism
 Journal metrics
See full report
Acceptance rate8%
Submission to final decision119 days
Acceptance to publication14 days
CiteScore5.200
Journal Citation Indicator0.480
Impact Factor2.2
 Submit Check your manuscript for errors before submitting

Article of the Year Award: Impactful research contributions of 2022, as selected by our Chief Editors. Discover the winning articles.