Metabolic Syndrome: Epidemiology, Pathophysiology, and Nutrition Intervention
1Department of Internal Medicine, University of Londrina, 86038-440 Londrina, PR, Brazil
2Department of Pathology and Clinical Analysis, University of Londrina, 86038-440 Londrina, PR, Brazil
3Department of Internal Medicine and Clinical Nutrition, University of São Paulo (USP), 14049-900 Ribeirão Preto, SP, Brazil
4Department of Biomedical Sciences and Physiology, University of São Paulo (USP), São Paulo, 14049-900 Ribeirão Preto, SP, Brazil
5School of Medicine , University of Southampton , IDS Building, MP887 Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
Metabolic Syndrome: Epidemiology, Pathophysiology, and Nutrition Intervention
Description
Metabolic syndrome (MetS) comprises pathological conditions that include insulin resistance, arterial hypertension, visceral adiposity, and dyslipidemia, which favor the development of cardiovascular (CV) diseases. Existing evidence suggests that MetS is rising in developed and in developing countries. Although obesity and insulin resistance comprise the leading causes of MetS, many other pathophysiological mechanisms, like proinflammatory adipocitokines, hyperuricemia, nitric oxide, and oxidative stress may contribute to the potential cardiovascular risk factors related to the syndrome. On the other hand, increases in anti-inflammatory adipocitokines, as adiponectin and antioxidant mechanisms, could give some CV protection. Nutritional intervention has been attempted to attenuate the detrimental or increase the beneficial mechanisms in order to decrease the potential risk of hypertension, glucose intolerance and diabetes, lipid disorders, and abdominal obesity, which are the main clinical features of MetS.
We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the pathophysiology underlying MetS and the development of strategies to treat these conditions through nutrition intervention. Potential topics include, but are not limited to:
- Prevalence and incidence of MetS around the world
- Advances in nutrigenomic of MetS
- Pathophysiology of MetS
- Identifying biomarkers of MetS
- MetS in children and adolescents
- Dietary patterns for prevention of MetS
- Nutritional intervention studies
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jnume/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: