Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice

Figure 4

Effect of CoPP and SnMP administration on insulin receptor-β, insulin receptor phosphorylated at tyrosine 1146, and insulin receptor phosphorylated at tyrosine 1322 protein levels in liver of lean and obese mice. (a) Total insulin receptor-β (IR-β) protein levels, IR-β phosphorylation at (b) tyrosine 1146, and (c) tyrosine 1322. Results are mean ± SEM of the bands density normalized to actin. -4, versus lean; versus obese; versus obese CoPP.

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