Effect of the Lipoxygenase Inhibitor Baicalein on Muscles in Ovariectomized Rats

Figure 6

Diameter and area of M. longissimus fibre types I and IIa and their relation to muscle weight and body weights. A significantly greater fibre type I size was noted in the C2 group than in the NON-OVX, the OVX group, and the C1 group ((a), ). A significantly greater fibre type IIa size was recorded for the C2 group compared with the NON-OVX and OVX groups ((b), ). Significant differences in the type I fibre area could be detected when the C2 group was compared with the NON-OVX and OVX groups, C1 group, and C3 group ((c), ). The fibre IIa area was significantly greater in the C2 group when compared with the NON-OVX and OVX groups ((d), ). Statistically relevant differences in diameter to body weight ratio were noted between the following groups. For type I fibres: NON-OVX versus OVX and the C1 group; OVX versus C2 group, C1 versus C2 group; and C2 versus C3 group ((e), ). For type IIa fibres, a significant difference was noted between the NON-OVX and OVX and between the OVX and C2 groups ((f), ). The OVX group showed a significantly less fibre to body weight index when compared with the NON-OVX group and C2 group. Moreover, the NON-OVX group showed a significantly higher index than the C1 and the C3 groups ((g), ). A significantly lower fibre area to body weight index was noted in the OVX group when compared with the NON-OVX and C2 groups. C2 group showed a higher fibre area to body weight index when compared with the OVX, C1, and C3 groups ((h), ). C2 group, when compared with the OVX group, showed a significantly higher fibre area to body weight index for the IIa muscle fibres ((i), ). , , and indicate significant difference.

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