Inflammatory and Oxidative Stress Responses to High-Carbohydrate and High-Fat Meals in Healthy Humans
Table 1
Baseline characteristics of study participants with (FH+) and without (FH−) a family history of T2D.
FH−
FH+
N (Male/Female)
7 (2/5)
8 (2/6)
Age (years)
41 ± 3
47 ± 2
Weight (kg)
BMI (kg/m2)
Total body fat (%)
36 ± 4
36 ± 4
Abdominal fat (kg)
Total cholesterol (mmol/L)
HDL cholesterol (mmol/L)
LDL cholesterol (mmol/L)
Triglycerides (mmol/L)
GIR (μmol min−1/kg FFM)
Glucose iAUC (CHO)
429 ± 65
492 ± 55
Glucose iAUC (Fat)
43 ± 13
53 ± 16
Insulin iAUC (CHO)
15924 ± 3190
31081 ± 3993*
Insulin iAUC (Fat)
1895 ± 392
3379 ± 322*
Data are given mean ± SEM, GIR: Glucose infusion rate necessary to maintain euglycemia during the hyperinsulinemic clamp; AUC: area under the curve, *.