Electrospun Collagen: A Tissue Engineering Scaffold with Unique Functional Properties in a Wide Variety of Applications
Figure 3
Dermal Reconstruction. Rates of wound closure in lesions treated with electrospun collagen (a) or electrospun gelatin (b). Note that increasing the extent of cross-linking has a modest effect on slowing wound closure and greatly increases total wound surface area in animals treated with electrospun collagen (a) and (c). Rates of wound closure were similar when injuries were treated with a wide variety of gelatin-based constructs (b) and (d). Panel (c) depicts the typical wound healing course for injuries treated with electrospun collagen in which approximately 70% of the available sites are cross-linked. Note the retention of wound surface area in this example. Panel (d) depicts the typical wound healing course for injuries treated with electrospun gelatin in which approximately 70% of the available sites are cross-linked. Note the classically X-shaped wound typical of a lesion that has undergone contraction.
