Electrospun Collagen: A Tissue Engineering Scaffold with Unique Functional Properties in a Wide Variety of Applications
Figure 2
Osteoblast interactions with electrospun collagen and electrospun gelatin. Human osteoblasts plated for 1 (a)–(d) or 8 days (e)–(h). Cells plated on electrospun collagen ((a), (e)), electrospun gelatin ((b), (f)), collagen gel ((c), (g)), or tissue culture plastic ((d), (h)). Cells plated onto electrospun collagen remain subconfluent after 8 days of culture (e) and accumulated phase bright crystals. At the ultrastructural level, osteoblasts plated onto electrospun gelatin expressed a rounded cell shape (i); when plated onto electrospun collagen, the cells were covered with elaborate arrays of plate-like structures typical of hydroxyapatite crystals ((j), (k)).
